Erectile Dysfunction
Erectile Dysfunction (Erection Problem) affects the lives of many middle-aged men and their partners to one degree or another. The term Erectile Dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity.
Cross-sectional epidemiological studies from around the world reveal that 30-50% of men aged 40-70 years report some degree of Erectile Dysfunction. About 150 million men worldwide are unable to achieve and maintain an erection adequate for satisfactory sexual intercourse. Age is the variable most strongly associated with Erectile Dysfunction; between the ages of 40 to 70 years, the incidence of moderate Erectile Dysfunction doubles from 17% to 34%, whereas that of severe erectile dysfunction triples from 5% to 15%.
When Erectile Dysfunction (Erection Problem) proves to be a pattern or a persistent problem, it can interfere with a man’s self-image as well as his and his partner’s sexual life. Erectile Dysfunction (Erection Problem) may also be a sign of a physical or emotional problem that requires treatment.
Latest pharmacological achievements in the treatment of Erectile Dysfunction (Erection Problem) have changed our understanding of sex around the world. Normal sex now means sex on demand, sex for everyone and sex for life.
These achievements represented a major cultural shift. In the post World War II era, medical doctors had admitted they could do little for men suffering from impotence, and most were therefore willing to accept the common belief that the vast majority of cases could be attributed to psychological disturbances. Psychoanalysis and sex therapists dominated the discussion of sexual problems through the 1970s. Sex counseling was moreover associated with the “sexual revolution” of the 1960s and the campaign for women’s “sexual rights”.
Sex therapists did deal with impotence, but many regarded their message, which stressed improving technique and communication, as female-oriented in both its methods and goals.
The 1980s saw the emergence of a new paradigm, a swing towards the medicalization of male sexuality.
The myth that Erectile Dysfunction is an irreversible consequence of ageing was put aside by these latest biotechnological developments.
For the first time in history doctors can offer men joy in the sexual arena, where little or nothing had been done for years.
Modern treatment options allow nearly every man to have a firm erection to ensure satisfactory sexual intercourse.
This satisfying sexual intercourse can restore and strengthen existing sex life, can lift depression associated with erectile dysfunction, can restore relationships torn by frustration, can return a man’s self confidence, can improve sexual and non sexual bonds with a partner, can restore intimacy and thereby deepen a relationship.
The development and wide spread acceptance of the effective oral Erectile Dysfunction (Erection Problem) therapies have enabled many patients with erectile insufficiency to realize their “fundamental rights… to sexual health” as established by the World Health Organisation.
Modern oral therapies are now well established and are effective treatments for millions of patients with Erectile Dysfunction (Erection Problem).
Oral treatments for Erectile Dysfunction (Erection Problem) however DO NOT meet the needs and expectations of all patients.
AMI offers patients a wide range of treatment options suited to their individual conditions and needs.
Whilst these options include some standard available treatments, our overall strategy is to convert existing drug products of known safety and efficacy profiles into a patient friendly dosage with a fast rate of absorption and rapid onset of action. Our goal is to offer increased patient satisfaction and avoid issues such as drug degradation in the gastrointestinal tract and side effects associated with some treatments.
Basic scientific investigations have shown that the natural history in most age-related Erectile Dysfunction (Erection Problem) begins with mild arterial insufficiency and progresses to more severe arterial damage and secondary corporal collagen and scar replacement. We believe that combination therapy is able to alter the natural history of the disease by promoting erections and thereby bringing oxygen rich blood to the corporal muscle. This may stop collagen and scar replacement of the corporal smooth muscle despite progressive worsening of the arterial supply. This will allow pharmaceutical agents to work for a longer duration of the patient’s life.